RAY EXLEY MD
co incidence is not proof of cause and effect. It might be a basis for suspicion, but proves absolutely nothing.
I do not know if the drug was responsible for the lymphoma, and neither to do you.
And I am not arguing that your conclusion is wrong or impossible, but my argument is that when more relevant data points are considered using the scientific method, the data does not support the conclusion of cause and effect, making that conclusion very unlikely.
I am sorry for your dog and your loss, as I have a very high affinity for nice dogs, and know the pain of loss.
However, the reported incidence of lymphoma appearing shortly after other doga took the drug is very very low, so that cause and effect which you seem to feel is proven, is actually not very likely.. This low reported incidence of this possible cause and effect, does Not prove anything about your dog, but if the drug caused your dogs disease, it is a very rare, thus unlikely event.
Applying scientific principles to the analysis of data often gets results which seems at odds with "common sense", but conclusions based upon the scientific analysis are much more likely to be correct than the apparently obvious common sense conclusions.
None of these observations proves or disproves your conclusion that the drug caused the lymphoma, but if that occurred the available data supports the conclusion that effect is very rare.
Unfortunately, scientific analysis is a very conservative way to analyze info, and it is often slow, and often seems to give results which are different that the "obvious" but scientific analysis is much more likely to be correct, than jumping to the "obvious" conclusion with only a one or a few data points. Statistical analysis of the data and the way it is processed will give good information about the probability of a conclusion is justified by the data, but don't bother in this situation as valid statistical analysis requires many more data points than the one you have noted in this situation, as the basis for your conclusion that this drug caused the lymphoma.
Sorry about your loss, but angst, pain about a co incidence are not a very good basis upon which to draw conclusions about the likelihood (probability) of cause and effect.