Will Falconer, DVM Moderator
Quite certain Dr. Cooney is referring to vaccine failure stats related to vet literature, so not likely home administered.
And as to nosode failure, if they are used properly, that's assured. Be sure to listen to the other two episodes linked at the end of the show notes for more on that.
As to efficacy of nosodes in Dr. Cooney's practice, listen again to the episode. He recalls the defining stink of parvo that used to greet him every morning on entering his ward and for the past many years, that is a distant memory since getting the practice's pups on a working nosode protocol.