Andrea
My dobe puppy had the 4 way shots at 7 and 9 weeks before I got him. He had nothing else before his titer at 5 years old and he showed antibodies to parvo, adenovirus and distemper no problem. I ended up telling the mobile vet I used for that when he was last vaccinated as a puppy as she said one was low and should be done the next year. No response from her!
The following year at 6 yrs old he had his first ever rabies July 4th, the 2 flu shots and bordatella 7 weeks later (both for moving to New Zealand) and died Nov 14th of cardiac hemangiosarcoma. He had his yearly full heart check the end of Feb that same year at the University of Guelph who have been doing a Doberman DCM study for decades. This includes 24 hr Holter exam, cardiac ultrasound and EKG and bloodwork. Nothing was seen abnormal in his heart then. My 2 yr old dobe I have almost died 6 months ago from rabies vaccinosis - again only done for moving to another country. Homeopathy with Dr Dym has helped him recover!